Not to play down anyone's stressful life experiences, but the sort of stress they're talking about in this article is more typically correlated with stressors like violence, hunger, or institutionalization in the first decade of life.
Surely the level of stress needed to have this impact is something that needs to be studied. The researchers presumably went to an extreme to ensure a clear signal for a result, but the fact they've shown there is a significant outcome the next step is to work out how much stress is needed to cause a long term problem.
You can't just dismiss the result because you think it's unlikely to be something that affects a lot of people.
There is a theory in transactional analysis therapy that states adult addiction (in all its forms) pretty much always stems from childhood trauma...
In a cable leaked by WikiLeaks in 2010, Amos Yadlin, former general of the Israeli Air Force, said in 2007 that Israel would be "happy" if Hamas take over Gaza and regarded it as a positive step, in order to make Gaza to be treated as a hostile state.
The details of money flow are complicated, but there are credible rumors of Israel funding Hamas via Quatar. There's a chance Hamas would have lost leadership to the Palestinian Authority had Israel not supported it during that era.
This is interesting and should make you think but it's the same issue with infiltrators/agitators in other groups. If all it takes for a group to start resorting to violence and eventually establishing as part of their identity the killing of "others", when instigated by some authority figure/small group of instigators - specially with lies and historical distortions - this itself points out that the nature of that group is problematic doesn't it?
Specially if that group has a history with thousands of terrorist attacks across all the world, even when just counting the last 25 years. It's the same if you join a left-wing group that's "just demanding" some social justice, as an undercover paid actor, and then you steer it to start killing people who are deemed "against" their objectives, or the reason they need to act. Then some people go and said they were "infiltrated", but was it so? Or was it just waiting for some nut case to come forward?
If I tell you to go kill all the cats in the neighbourhood and you go, you're as or more dangerous than I am for suggesting that isn't it so?
While I'm sure Israel is no angel it doesn't seem to be the one putting criminals in hiding near schools and civilian infrastructure and I also don't understand what people want them to do? Have no country?
So others can then do with them as they please? Like telling them to "go back to their country". While it's obviously all part of a political ploy, jews should have a right to a homeland. No-one talks about Egypt and the other surrounding countries interests in this, in having a "Palestine" identity that didn't even exist a few decades ago. In fact, if you go see the first declarations, made by some Turkish guy, looking like the brother of Abramovich, sent to Palestine at the time, there's not even mention of anything Palestine.
And lastly, it's very rich to live in countries that have benefitted from this (oil) and follow ways of life that require this, while sipping on their $15 expresso's machiatos... So in fact, perhaps there's many called "humanists" in the west that have way more blood in their hands than they would like to understand, or pretend not to, while filling their wallets and living as good samaritans. Maybe they should globalize intifada next to their homes to see if they also like living like that.
This is not to say that Israel should have the right to bulldoze, kill and take lands of others for building high-rise apartment complexes but as far as I know and seems to be documented, it was the supposed Palestinian Authority's that many times refused land agreements and split-state solutions... But I guess here in this website where most were covid infected it doesn't matter.
> Sure, never mind the millions of jews in concentration camps. Or what about the jews being terrorized by the likes of hamas, al-queda, taliban, al-shebab, IS, or any other islamic terror organization worldwide? Over the past 80 years, the number of children involved may dwarf the figure you got from hamas.
the levels of shamelessness here on display here is breathtaking...
Just forgot that the Gaza oppression is ongoing, with the perpetrating govt still making claims on escalating it further, and the ww2 concentration camp oppression was stopped ~80 years ago.
Both are bad. But thinking that there is a connection between the two is indeed olympic-level mental gymnastics.
At least in ww2 perpetrating govt tried to hide it because they knew the ordinary citizens would not take it lightly. In the current case ordinary citizens climb hills to watch and rejoice.
hmm inquisition, conquistadores in south america, and british expansion into india, the genocide of the kumir ruge and congo under leopold and the holocaust had nothign to do with islam.
atheist here, from my perspective, all the religions seem to lean in teh direction of violence when paired with a greedy elite.
also have you read the old testament? large sections of it come down to "god told us to kill them so we did down to the last sheep"
All the clichés... You don't even know what you're talking about. Go see a map of india when the first european country arrived there. Go see the history of hormuz, go see how even 30/40 years ago indigenous tribes in Brazil would set "hunting seasons" where they go out to kill other tribes. You think that the local natives in much of these countries allied with completely alien looking foreigners for what reason?
You must also think that it was the europeans that invented slavery, and that islam wasn't the culture that trafficked more africans than anyone else in history, even with rudimentary transportation and logistics - yeah they didn't do Atlantic because Allah forgot to tell them about half the world. Go see africa and the wars, still raging today, perpetuated by the good boy muslims - all started even before any european set foot there. Just Mozambique for instance. Or in Thailand, or in Bali, or I don't know, so many other countries.
Inquisition? Most natives in the supposed countries where inquisition was put outside of Europe preferred to be judged by the Inquisition than by their, you guessed it, non-existing judicial systems and the inquisition only had authority over christians - that is, people who declared themselves christian, for various reasons mostly related to access to political and administrative positions but while professing having become christians didn't (since they kept behaviours, rules and laws between themselves opposing christian values).
Islamophobia is the symptom of people who don't want a religion who's most revered figure is a PDF who fucked an 8 year old while already having a bunch of wives, whose God doesn't seem to understand how the human body works to top it off and keeps lying about its own history, motivations and actions.
Your problem is that you neither know, nor talked with anyone who lived, or lives in those situations that is not well educated or a man. Go see what happens beneath the yam yam and the humbleness of the dressing in countries like indonesia (which is considered "soft" islam, with exception of Aceh). But you come on the internet pontificate like you know anything other than what your rot-by-media-brain, paid with oil & blood money wants you to believe.
While you may say that the old testament, or new testament has things that are contradictory (specially the old testament) in no way did those configure the societies where they exist in the same way as muslim societies end up being. In fact, all contemporary progressivism is easily traceable to Christianity, specially the Catholic Church.
Atheists are responsible for the biggest number of mass killings in history - in part due to technology in part due to modern warfare. And the society you built is one where depression, aggression, addiction and just general retardedness is higher than everywhere else. Imagine doing a full cycle of public education and ending up with this general knowledge of the world, peddling covid and unable to even understand the most basic things even when it's right in front of them.
While you say holocaust had nothing to do with Islam, Hitler professed his admiration for Islam as he saw christianity as weak.
I do hope that those that defend it end up tasting it right up their alley, their homes, or their families, because if it's so inoffensive this shouldn't read like a threat but wishes of a good future.
Not a scar IMHO, but a wound that can be healed. SETD7 is a Histone Methyltransferase. Meaning it attaches methyl groups to DNA which turns genes off. But there are enzymes that remove these methyl groups as well and they are called Demethylases [1]. Many of these enzymes can be stimulated by their nutritional cofactors which are things like Zinc, Iron, and Riboflavin.
I am a product of early life trauma. Knowing these thing have helped me tremendously.
I remember having it drilled into me in High School that unless you did well on your finals:
1. You wouldn’t get the score you needed to get into a good University and/or accepted into the course you wanted.
2. If you didn’t get into that course, you wouldn’t be able to do <x> for a career.
3. If you DID get into the course you wanted, it needed to be at a top University (which of course required an even higher entry score) or else you’d find it hard to get a job afterwards.
Imagine all of that stress: Telling 16-18 year olds that unless you ace your tests, you won’t be able to do what you want to in life.
The optimal amount of stress about that stuff is not zero, and most teenagers are going to be desperately biased towards "none of this matters, just peermax".
Couldn't some of that because of how people act like EVERYTHING is the most important thing for kids to do, irregardless of how it actually stacks up, and some develop something akin to alarm fatigue and stop listening?
Plus almost everyone can get into a college, there is only really competition for a handful of elite schools. My college wanted SAT scores for admission, I did not take the SAT, they still admitted me without question. As long as you don't fail out your first two semesters in a row most colleges don't give two craps about your highschool performance.
I remember having it drilled into me in high school that I was procrastinating school work while at my mom's to avoid spending time with my dad and I was faking my sobbing for sympathy and I was a horrible person who was lucky to have a dad as good as I had and how I keep doing the same things wrong and I am a smartass prick who doesn't care about anyone but myself.
12-14 was rough.
School work stress was quite tame by comparison. At least your teachers don't scream at you for hours until you forget why.
It's called "Adverse Childhood Experiences", or ACEs, and the field of psychology has found them to be extremely good predictors of future negative outcomes for a long time now.
Things like abuse, neglect, natural disasters, basically anything that can cause trauma or significant stress.
Be a toddler and your mom's new boyfriend abuses both of you? Congrats, you brain has developed in a way that will not be conducive at all to your future, because instead of developing a functional reward system, you've developed a specific hyperawareness to manage the difficulty of living around one kind of abuser. This incredibly specific adaptation will of course, not prevent you from being an easy target for an entirely different type of abuser in high school.
(It's actually not that simple of course. Multiple ACEs are predictive of future troubles, not just one, so it's more like "A child who lives in an environment of constant stress, fear, and pain is likely to have a brain that didn't develop well" with a direction of effect unstated)
This is one reason why things like abuse and poverty are so damn cyclical. Your parents grew up in poverty and with abusive parents, so they have an elevated chance to abuse their children, and on and on and on.
This is also one reason why something like "Free food at school for anyone who wants it" is so damn effective, because it eliminates an entire class of ACEs from all those kids, and in the US, it also eliminates the horrific humiliation machine we've built around paying for school lunch, which might not be the best way to raise kids anyway.
It takes a village is so true. Children are something society as a whole should invest in, and fails to do so at risk to it's own future.
By society, I mean every one of us that plans to grow old instead of an early death.
Wouldn't it be nice to have two or three or ideally more generations of well adjusted people that grew up not fearful of hunger, nor lack of basic shelter, medical care?
Also, providing quality child care for any time the parent(s) are working frees up quality workers to do that... though a better work life balance would also help society.
Just FYI, that type of stress is typically not included as a form of Adverse Childhood Experiences (ACE). That does not mean I think it does not matter. It does, and more so for kids with poor diets.
My childhood ACE's: Woke up on an operating table when I was three, mother and brother attempted suicide, Mother with schizoaffective disorder, physical abuse by my brothers, psychological torture by my brother (he forced me to watch him burn a nest full of baby birds with a blow torch).
I was utterly convinced at age 14 that I had ruined my life and any chance of a good career. I also was pretty sure the world was going to end soon. I started smoking cigarettes and experimenting with various risky behaviors. A few years later, I became suicidal for a time.
It wasn't until my late 20s that I started living a more 'normal' life, but by then I was a decade behind in career development and other things.
Academic concerns may not by themselves count as trauma, but combined with other factors they can be the thing that pushes someone into total hopelessness.
Exam pressure isn't the kind of stress they're talking about.
>> More than half of the world’s children are exposed to early-life stress from abuse, household dysfunction such as violence or drug use, or other traumatic experiences
"In mice" is the right caveat for outcomes and the wrong one for mechanisms. Nobody’s selling you a drug here--they’re describing a chromatin change, and that’s the part rodents are actually good for.
The alternative study design is randomizing infants to early-life stress and biopsying their hippocampi at 30. Committee’s still reviewing it.
These pop-sci articles annoy me greatly. All I can think reading the title is “well, duh?” - they’re a complete tautology.
Let me explain: if an event or behaviour affects a person, it means that there must be a physical record of it. These types of articles confirming that such a record has been found might be great news for researchers, but for everyone else, the existence of this physical record was already known a priori. We are biological machines after all, all behaviours are encoded physically.
If there was no such scar in brain cells, there would have been no early-life stress.
This applies to other research such as “learning changes structure of the brain” or “drug addiction turns off specific neural pathways” or “brains of children with autism differ from neurotypical brains” or “athletes have more developed muscles”
> if an event or behaviour affects a person, it means that there must be a physical record of it
Yes, and it (or at least one of them) has now been found. Maybe you don't care about knowledge for its own sake, but as the "irritating" press release goes on to point out,
“There are currently no treatments for what early-life stress does to the brain, partially because we have not had a clear picture of what molecular mechanisms to target,” Peña said. “This work is exciting because it reveals a clear mechanism, and also helps explain why the impact of stress is both latent and broad.
We do all know experience has its substrate, but one thing matters more—are they encoded as stubborn neural connections, mitochondrial damage, epigenetic marks, or something else to transform it into depression, long-term inflammation, or stress susceptibility, etc.? The current evidence emphasizes epigenetics. Only if we know what the 'it' is, do we have chance to change, rather than just knowing it exists.
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